By the age of thirteen, Anna has undergone countless surgeries, transfusions, and shots all so her older sister, Kate, can somehow fight the leukemia that has plagued her since childhood. Anna was conceived as a bone marrow match - a life and role that was never questioned - until now. Like most teenagers, Anna begins to question who she really is, but unlike most teenagers, she has always been defined in terms of her sister - and so Anna makes a decision that for most would be unthinkable ... a decision that will rip her family apart and have fatal consequences for the sister she loves. Told from multiple points of view, My Sister's Keeper examines what it means to be a good parent, a good sister, a good person. Is it morally right to do everything possible to save the life of a child ... even if it means violating the rights of another? Should you follow your heart, or allow others to lead you? What happens when emotion catches up to scientific progress?